What Is NeoMag and Why Is It Different?

A deep dive into how NeoMag is revolutionizing biomedical research with non-invasive mechanical stimulation.

When traditional research methods fall short in replicating the complexity of biological tissues, innovation becomes essential. Enter NeoMag, the first patented magneto-mechanical platform developed by 60Nd—a spin-off from Universidad Carlos III de Madrid—that provides non-invasive, precise, and dynamic mechanical stimuli to cells and tissues in vitro.

🔍 Why NeoMag Matters in Biomedical Research

Cellular processes in our body are heavily influenced by mechanical forces. However, most in vitro models fail to incorporate these critical mechanical stimuli, resulting in limited predictive power for real-world biological responses. NeoMag bridges this gap by:

• Non-invasive Mechanical Activation: Stimulates cells without direct physical contact, avoiding potential damage or contamination.
• Complex Biological Simulation: Replicates a wide range of dynamic mechanical environments, essential for accurately studying biological processes.
• Compatibility and Integration: Seamlessly integrates with conventional imaging systems (confocal microscopy, fluorescence imaging) and instrumentation equipment like nanoindenters.
• Versatile 2D & 3D Systems: Adapts easily to different biological models such as monolayer cultures, organoids, and tissue fragments.

🧠 Key Applications of NeoMag

NeoMag’s versatility makes it an invaluable tool across diverse research areas:

• Wound Healing: Simulates mechanical conditions essential for fibroblast migration and extracellular matrix remodeling.
• Cancer Research: Mimics mechanical cues influencing tumor progression and metastasis.
• Neuroscience: Reproduces conditions seen in traumatic brain injury (TBI) to understand cellular responses and potential treatments.
• Cardiac Health: Models cardiac tissue remodeling post-myocardial infarction, providing insights into cellular mechanotransduction.

🚀 What Sets NeoMag Apart?

NeoMag is uniquely positioned due to its:

• Integration of Smart Materials & AI: Uses advanced computational models and machine learning to optimize mechanical stimulation protocols.
• Reduced Research Costs and Risks: Enables researchers to identify potential therapeutic failures early, streamlining the drug development process.
• High-Quality and Reproducible Results: Offers consistent control and reproducibility, crucial for translating research into clinical applications.

📈 Real Results & Early Validation

NeoMag is already used by leading research institutions globally, including UCSF, Imperial College London, and Johns Hopkins University. A case study in brain trauma demonstrated significant changes (>50%) in cell stiffness, actin remodeling, and altered calcium signaling under mechanical stress, validating NeoMag as a critical tool for mechanobiological research.

🎯 Why Now?

The biomedical industry is increasingly recognizing the importance of mechanobiology in therapeutic development. NeoMag is perfectly timed to support the urgent need for physiologically relevant models, addressing a vast market with intersecting interests in regenerative medicine, drug discovery, and laboratory equipment—collectively worth over $300 billion and growing at a CAGR of 7.6%.

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